Short-term cardiometabolic risk reduction after bariatric surgery.

نویسندگان

  • Justyna Domienik-Karlowicz
  • Olga Dzikowska-Diduch
  • Wojciech Lisik
  • Andrzej Chmura
  • Piotr Pruszczyk
چکیده

INTRODUCTION Clinically severe obesity, defined as a body mass index (BMI) 40 kg/m2, increases cardiovascular risk and results in elevated mortality. The objective of this study was to examine the short-term health benefits after bariatric surgery. Using commonly recognized scoring systems, we assessed the shortterm reduction of calculated cardiometabolic risk following bariatric surgery. METHODS Short-term cardiovascular risk reduction was assessed prospectively in 50 consecutive, morbidly obese patients (45 women, 5 men, age 39.3 ± 8.97 years, BMI 50.67 ± 12.25 kg/m²) using the following scales: the Finnish Diabetes Risk Score, Reynolds Risk Score, Italian "Progetto Cuore" score, SCORE. The follow-up data at baseline and six months were recorded in all studied patients. Patients who did not meet the inclusion criteria of particular score systems were not included in the analysis. There were no revisions, surgical failures or deaths in the study group. RESULTS The average weight loss six months after bariatric surgery was 35.8 ± 10.59 kg (mean BMI 36.54 ± 5.92 kg/m²). The most interesting result was that the median value of a 10-year risk of developing type 2 diabetes according to the FINDRISC score was 15 (IQR 15-15) at baseline vs. 13 (IQR 13-13) following surgery, p<0.001. We observed a reduction of 2 points in the majority of patients. In addition, in 29 patients it was possible to calculate the 10-year probability of developing the first major cardiovascular event using the Italian "Progetto Cuore" score; the median score decreased from 2.0 to 0.8 (p<0.001). CONCLUSIONS Weight loss at 6 months, as a result of bariatric surgery in this group of clinically severely obese patients at a very high risk, was especially effective as concerns the reduction of the calculated risk of diabetes, cardiovascular diseases, and related mortality.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bariatric Surgery Reverses Metabolic Risk in Patients Treated in Outpatient Level

BACKGROUND The conventional treatment of obesity presents unsatisfactory results on weight loss and its long-term sustainability, therefore bariatric surgery has been suggested as an effective therapy, determining sustainable long-term weight loss, reversal of components of cardiometabolic risk and improved quality and life expectancy. AIM To investigate the clinical component of the cardiome...

متن کامل

An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery

Bariatric surgery is currently one of the most effective treatments for obesity and leads to significant weight reduction, improved cardiovascular risk factors and overall survival in treated patients. To date, most studies focused on short-term effects of bariatric surgery on the metabolic profile and found high variation in the individual responses to surgery. The aim of this study was to ide...

متن کامل

Emerging pharmacotherapy for treating obesity and associated cardiometabolic risk.

The global obesity epidemic is causing much concern among health professionals due to the major health risks associated with obesity. Excess weight, particularly abdominal obesity, elevates multiple cardiovascular and metabolic risk factors, including Type 2 diabetes, hypertension, dyslipidaemia and cardiovascular disease. Thus obesity management goals should encompass health improvement and ca...

متن کامل

Effect of bariatric surgery on adiposity and metabolic profiles: A prospective cohort study in Middle-Eastern patients

AIM To investigate changes in adiposity and cardio-metabolic risk profile following Roux-en-Y gastric bypass in patients of Middle Eastern ethnicity with severe obesity. METHODS This prospective cohort study involved 92 patients who met the indications of bariatric surgery. Post-procedure markers of obesity and cardiometabolic profile were monitored regularly for a year. RESULTS Mean body m...

متن کامل

Investigating Changes in the Serum Iron, TIBC (Total Iron Binding Capacity) and Transferrin Levels in Patients with Morbid Obesity Undergoing Bariatric Surgery in Kerman in 2018: A Short Report

Background and Objectives: Bariatric surgery is one of the most effective treatments for obesity. This study was designed to investigate changes in the serum iron, TIBC (Total Iron Binding Capacity) and transferrin levels in patients with morbid obesity undergoing bariatric surgery in Kerman in 2018. Materials and Methods: This prospective study was carried out on 65 participants who had gone ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

دوره 56 1  شماره 

صفحات  -

تاریخ انتشار 2015